ea0029p1792 | Thyroid cancer | ICEECE2012
Pupilli C.
, Pinzani P.
, Salvianti F.
, Fibbi B.
, Rossi M.
, Petrone L.
, De Feo M.
, Forti G.
Introduction: Although overall accuracy of fine needle aspiration (FNA) in identifying thyroid cancer is considered excellent, 2030% of aspirates do not allow definitive diagnosis of malignancy. Proto-oncogene somatic mutations such as BRAFV600E in FNA strongly suggest the presence of malignancy. However, only few studies reported the use of circulating BRAFV600E-mutated alleles in plasma as an useful marker for non invasive diagnosis and follow up of this disease.<p...